You might have to take a little bit of time off, but that's a small price to pay to avoid permanent disc damage or possible surgery. (bodybuilding.com)
Extreme (but plausible) results of sitting for extended periods of time include: heart disease, overproductive pancreas, colon cancer, foggy brain, strained neck, sore shoulders and back, mushy abs, tight hips, limp glutes, inflexible spine, disc damage, poor circulation, and soft bones. (bostonmamas.com)
This in turn can lead to disc damage, nerve root irritation, joint degeneration or muscle overload / tightness / pain. (mindbodygreen.com)