Previous studies have managed to identify more than 40 distinct genes in humans which are linked to genetic kidney disease, but our understanding of their precise roles in kidney function is very limited. (frontlinegenomics.com)
However, the MIT team adapted it to randomly turn on or off distinct gene sets across large populations of cells, allowing the researchers to identify genes that protect cells from a protein associated with Parkinson's disease. (sciencedaily.com)
In all, we found 900 probes from 448 distinct gene promoters whose normalized intensities were significantly associated with chronic aggressive behavior (FDR < 0.2, Spreadsheet 1). (journals.plos.org)