It is a motor disorder caused by the loss of dopaminergic neurons in the black substance of the brain. (sciencedaily.com)
We also observe a significant loss of dopaminergic neurons in the substantia nigra pars compacta 60 days after infection. (pnas.org)
An overactive immune system due to dysfunctional PINK1 and Parkin genes could explain why dopaminergic neurons die in Parkinson's patients. (fullhealthsecrets.com)