This would essentially show the effect of genetics in a quasi dose dependent manner. (sciencedrivennutrition.com)
The phase 1 / 2a study of IONIS - HTTRx was recently completed and showed the therapy to be safe and well - tolerated but also showed it's ability to reduce the level of mutant huntingtin in a dose dependent manner in Huntington's Disease patients. (ehdn.org)
Further investigation showed that DHEA shortens the period of the circadian clock in cultured human cells in a dose dependent manner. (scicasts.com)