A new study shows that the cancer drugs imatinib (also known as Gleevec by Novartis) and sunitinib (Sutent, made by Pfizer) halt diabetes in mice. (scientificamerican.com)
Ninety - five percent of affected patients can be treated successfully with the Novartis drug imatinib, also known as Gleevec ®. (sciencedaily.com)
The current study showed that HIF - 1α inhibitors, specifically the cancer drug imatinib (Gleevec), the natural product apigenin, and the small molecule PX - 478, potently inhibit dysregulated BMP signaling induced by HIF - 1α in cells, as well as heterotopic ossification following tissue injury in a mouse model of FOP. (sciencedaily.com)