Generally speaking, contract negotiations go better when the series of counter offers involve the minimum changes from the most recent necessary to effect the desired resulting changes. (law.stackexchange.com)
Simply combine the existing molecule with another substance that interacts with it, and the transient forces between them can effect the desired change. (scientificamerican.com)
GF A side effect is an effect occurring in addition to the primary (or main) effect desired during the application of a treatment for a given indication. (graffuturism.com)