Even though they're only applied to the skin, excessive application increases the risk of skin infections or the skin can become excessively thin. (smartdogowners.com)
China has been called out in the news numerous times in the past few years for its poor environmental and waste management practices, excessive application of chemicals and fertilizer, and lack of government and food safety regulations. (northcoast.organic)
The chief threats to water quality posed by agriculture are: high organic fertilization levels in combination with high stocking rates, the excessive application of mineral N - fertilizers; the lack of a protective soil cover; narrow crop rotations and frequent tillage; high levels of available nitrogen after harvest, and contamination of water with synthetic pesticides. (fao.org)