To identify segments across the intronic and exonic regions of the BRCA1 or BRCA2 genes associated with different breast vs ovarian cancer risks, we created bins of mutations by base pair location (Figure 1). (jamanetwork.com)
Cáceres, E.F, Hurst, L.D. (2013) The evolution, impact and properties of exonic splice enhancers. (ettemalab.org)
Notably, the de novo mutation rates in this study were higher in exonic regions regardless of the paternal age. (massgenomics.org)