Loss of the PBRM1 gene function caused the cancer cells to have increased expression of other genes, including gene pathway known as IL6 / JAK - STAT 3, which are involved in immune system stimulation. (sciencedaily.com)
ZNF804A also interacts with and modulates expression of other genes known to be associated with schizophrenia. (sciencedaily.com)
The activity of four transcription factors — proteins that regulate the expression of other genes — appears to distinguish the small proportion of glioblastoma cells responsible for the aggressiveness and treatment resistance of the deadly brain tumor. (sciencedaily.com)