We would have no way of nothing that he had hemophilia without the circumcision-most families have a family history of the disorder, but our case, and 30 % of cases are, was a random genetic mutation. (live.happybottomus.com)
These include functioning successfully in their lives before the disease emerged; experiencing severe symptoms suddenly, all at once, rather than little by little; being older when the disease appeared; being female; having a higher IQ; and lacking a family history of the disorder. (scientificamerican.com)
Although ASD is heritable, children with no family history of the disorder can still develop it through genetic mutations. (discovermagazine.com)