He quickly helped develop the first mouse model of retinoblastoma, identified potential new treatments for the disease, and moved new therapies into clinical trials. (sciencemag.org)
In a new study, researchers led by a molecular biologist at the University of California, San Francisco (UCSF), report two breakthroughs in understanding those lesions and their role in pancreatic cancer: the development of the first mouse model that simulates a precursor lesion called intraductal papillary mucinous neoplasia (IPMN), and the identification of an enzyme, Brg1, that appears to help cause the formation of IPMN lesions while also suppressing another precursor lesion. (sciencedaily.com)
This resulted in the recovery of the first mouse models of HLHS. (sciencedaily.com)