B, the expression of endogenous p21waf1 / cip1 is enhanced by forced expression of DDX3. (cancerres.aacrjournals.org)
Daley and Urbach's team found that they could reverse Lin28's tumor - causing effects in their transgenic model by forcing expression of Let - 7, suggesting that treatments targeting Lin28 hold promise for treating Wilms tumors. (sciencedaily.com)
We also show that AKT activation contributes to mTOR phosphorylation, at least in part, as forced expression of constitutively active AKT by myristoylated AKT adenovirus results in increased phosphorylation of mTOR and its downstream effectors. (cancerres.aacrjournals.org)