Of the more than 300 rare and low frequency difference we found, 74 appear to affect the structure of proteins. (sciencedaily.com)
To identify signatures of geographically restricted natural selection, the authors searched for DNase I peaks containing variants with significant allele frequency differences between individuals of African, European, and Asian ancestry. (massgenomics.org)
Allele frequency differences between groups in India are larger than in Europe, reflecting strong founder effects whose signatures have been maintained for thousands of years owing to endogamy. (nature.com)