It is likely to take many generations to reduce the frequency of this disease in breeds with higher frequency of the mutation. (siriusdog.com)
A similar frequency of this mutation may be detected in dogs from other geographic areas. (awca.net)
The cancers share a high frequency of mutations in TP53 (between 84 and 96 percent) and a low frequency in PTEN, with only 1 to 2 percent mutated. (genome.gov)