Your feet are your most frequent point of contact with the earth, this means that whatever is happening at ground level will affect EVERYTHING higher up, pelvic floor included. (bodyandbirthphysio.com)
The speeding law is one of the most frequent points of contact between the public and «the law,» I'd say. (slaw.ca)
The genes responsible for these proteins undergo frequent point mutations, resulting in genetic «drift»; moreover, the genes from different animal and human strains may also interchange, resulting in genetic «shift.» (scientificamerican.com)