An added benefit is not proven, as no suitable data are available, neither for the direct nor for the indirect comparison of dimethyl fumarate with the appropriate comparator therapy. (sciencedaily.com)
A combination of two HIV drugs, tenofovir disoproxil fumarate and emtricitabine, sold under the name Truvada, was approved by the Food and Drug Administration for daily use as pre-exposure prophylaxis, or PrEP, in the U.S. in 2012 to help prevent HIV infection. (sciencedaily.com)
In such a network it is possible to compare dimethyl fumarate with beta - interferon 1a without the two drugs having been investigated in a common study. (sciencedaily.com)