Analytical methods for inferring functional effects of single base pair substitutions in human cancers Human Genetics DOI: 10.1007 / s00439 -009-0677-y (massgenomics.org)
In contrast, genetic variation that increases one's risk for neurodegenerative diseases, such as Alzheimer's and Parkinson's disease, shows a striking enrichment of functional effects in monocytes. (sciencedaily.com)
Indeed, patients» autoantibodies have structural and functional effects on the target antigens by a mechanism of antibody - mediated internalization of the antigen. (inmg.fr)