This is partly because the leading pharmaceutical therapy for osteoarthritis, non-steroidal anti-inflammatory drugs, can cause problems like gastrointestinal ulceration in some dogs. (ipupster.com)
A water mold infection called pythiosis is also known to trigger gastrointestinal ulceration, as is infection with helicobacter bacteria. (vetdepot.com)
Antacids may be given prophylactically to prevent gastrointestinal ulceration. (texaswestveterinarian.com)