"General irritability" refers to a state where someone easily gets annoyed or grumpy without any specific reason. It means they are frequently irritable or easily bothered by small things. Full definition
The symptoms of the exit of the molars are the same as with the smaller teeth and include general irritability, drooling and sleep disorders. (teethfever.com)
Baby sleep problems have been linked to emotional and behavioral problems, accidental injuries, and general irritability in babies as you probably already know. (get-your-baby-to-sleep.com)
If your little one is struggling with sleep, upset tummy and general irritability due to teething, Balm Baby's Bye Bye Teething Hello Sleep is a soothing tincture that will calm baby down and allow her to rest (pinstripesandpolkadots.com)