Analogue studies limit generalisability in several ways. (ebmh.bmj.com)
Analogue studies therefore maximise the internal validity, or rigour, of research studies; the trade off for this rigour is reduced generalisability to real clinical settings.2 Thus, an analogue outcome study of psychotherapy might recruit university students with symptoms of depression to compare the efficacy of brief cognitive therapy from a clinical psychologist with treatment as usual from the university counselling centre. (ebmh.bmj.com)
With this, the working group at the MedUni Vienna has also achieved a better generalisability of the research results so far with regard to working memory and attention in patients with multiple sclerosis. (sciencedaily.com)