Hamster TRPM8 proteins also lost their cold tolerance with slightly different genetic tweaks in the same region of the gene. (sciencenews.org)
They have used the technology to investigate whether specific genetic tweaks to immune cells» DNA could increase resistance to an HIV infection. (gladstone.org)
The team built a high - throughput cell - editing platform using a variant of CRISPR / Cas9 technology that allowed them to test how well scores of different genetic tweaks defended immune cells against HIV. (gladstone.org)