«Some of these off - target genome modification events will likely lead to negative biological consequences.» (newscientist.com)
This will allow easy preimplantation genetic diagnosis on a large number of embryos — or easy genome modification for those who want edited embryos instead of just selected ones.» (scientificamerican.com)
Could Cas9 - DOG be developed soon to allow genome modification only in a small subset of cells? (blog.addgene.org)