Despite the clear importance of 3D genome organization to basic and medical research fields, genome - organizing mechanisms and their functions in distinct nuclear processes are poorly understood. (wistar.org)
The team discovered that the pattern of differences in genome organization between various individuals of the same species indicates that the bacteria transfer DNA, including whole genes, back and forth. (sciencedaily.com)
More specifically, we have been studying the roles of the condensin and cohesin complexes in 3D genome organization in the fission yeast, mouse and human systems. (wistar.org)