The team's results uncover a previously unknown, complex genomic landscape of this cancer, which can be used to design new personalized drug regimens for SS patients based on their unique genetic makeup. (sciencedaily.com)
With accelerating development of personalized cancer treatments matched to a patient's DNA sequencing, proponents say frontline physicians increasingly need help to maneuver through the complex genomic landscape to find the most effective, individualized therapy. (sciencedaily.com)
Dr. Loftus» current research integrates the identification of these types of epigenetic modifications that mark the melanocyte regulatory genomic landscape with regulatory protein and transcription factor chromatin - binding domains, thus defining groups of non-coding DNA sequences utilized in the control of melanocyte gene expression. (genome.gov)