How lithium stabilises mood is poorly understood but when the scientists investigated how it prolongs the lives of flies, they discovered a new drug target that could slow aging — a molecule called glycogen synthase kinase - 3 (GSK - 3). (sciencedaily.com)
How lithium stabilises mood is poorly understood but when the scientists investigated how it prolongs the lives of flies, they discovered a new drug target that could slow ageing — a molecule called glycogen synthase kinase - 3 (GSK - 3). (ucl.ac.uk)
In particular, chemical inhibitors of glycogen synthase kinase 3 (GSK - 3) were found to elevate SMN levels by stabilizing the protein. (smafoundation.org)