His project asks a new question that explores the potential benefits of mTOR inhibition as a means of extending healthspan of our skeletal system. (buckinstitute.org)
The role of the gut, which is significantly altered upon dietary manipulation, remains poorly understood in DR.. Our preliminary data suggests that changes in gut function and physiology in response to DR play a key role in modulating healthspan in Drosophila. (buckinstitute.org)
Together these aims will help to decipher the α - DC detoxification network and identify therapeutic targets and novel compounds that can mitigate diabetic complications and extend healthspan of diabetics. (buckinstitute.org)