The process enables some viruses to insert their genetic material into the DNA of healthy human cells, which can lead to tumors and other diseases. (sciencemag.org)
Healthy human cells typically turn on nearly half of their 20,000 genes at any given time, and they choose those genes carefully to produce the desired cellular responses. (sciencedaily.com)
They then mimicked the effects of such mutations in lab dishes by systematically inactivating each of these cancer - associated genes in healthy human cells, creating 625 different perturbations that mirrored distinct genetic mutations seen in real breast and ovarian cancers. (sciencedaily.com)