Zhang used surface plasmon resonance spectroscopy to measure aspects of the interaction such as the rate at which the two molecules bound together, the strength of their interaction, and the molecular structure of heparan sulfate required for a successful interaction. (sciencedaily.com)
Over the course of the study, patients will attend up to nine clinic visits where they will have the level of heparan sulphate in the spinal fluid measured, as well as undergoing physical examinations and other assessments. (sciencedaily.com)
In its active form, it functions to regulate levels of heparan sulfate, a kind of generic cell membrane receptor. (sciencedaily.com)