Nakano S, Nagasawa T, Ijiro T, Inada Y, Tamura T, Maruyama K, Kuroda J, Yamazaki Y, Kusama H, Shibata N. Bezafibrate prevents hepatic stellate cell activation and fibrogenesis in a murine steatohepatitis model, and suppresses fibrogenic response induced by transforming growth factor - beta1 in a cultured stellate cell line. (researchdiets.com)
Tumor necrosis factor - a promotes cholestasis - induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase - 1 production in hepatic stellate cells. (abcam.com)
In their study, the researchers explored the possible connection between NOX1 and NOX4 and the activation of hepatic stellate cells (HSCs), which are known to be key players in liver scarring. (sciencedaily.com)