This protease activates hepatocyte growth factor (HGF) and urokinase plasminogen activator (uPA), two proteins thought to be involved in the growth and motility of cancer cells, particularly carcinomas, and in the vascularization of tumors. (link.springer.com)
We recently demonstrated that crosstalk between c - met / hepatocyte growth factor receptor and the alpha2 beta1 integrin contributes to mast - cell activation. (vicc.org)
Hepatocyte growth factor ameliorates acute graft - versus - host disease and promotes hematopoietic function. (cellr4.org)