The data below shows the overlap between the cytokines that are altered with normal aging and the ones that are altered in heterochronic parabiosis experiments (reference): (anti-agingfirewalls.com)
Large differences in staining for these cell markers were not observed in heterochronic young mice compared with isochronic young mice. (scienceintheclassroom.org)
This approach is rooted in the century - old concept of heterochronic parabiosis, whereby exposure of aged tissues to young factors can extend organismal lifespan and improve aged tissue function. (edbosarge.com)