In addition, the authors found a strong association between pre-existing joint disease and development of peri-articular histiocytic sarcoma in the same joint, particularly when the stifles or elbows were affected. (vrcc.com)
Other breeds that have an increased incidence of histiocytic sarcoma include flat coat retrievers, and Rottweilers. (vcsspdx.com)
Most dogs with histiocytic sarcoma are middle aged or older, but this cancer has been reported in dogs as young as three years old. (vcsspdx.com)