"homozygous mutations" refers to when an individual has two copies of a gene with the same abnormal or altered version, resulting in a genetic mutation. Full definition
Homozygous mutations in VAMP1 cause a presynaptic congenital myasthenic syndrome We report 2 families with undiagnosed recessive presynaptic congenital myasthenic syndrome (CMS). (rd-neuromics.eu)
«We show that diploids adapt more slowly than haploids, that ploidy alteres the spectrum of beneficial mutations, and that the prevalence of homozygous mutations depends on their genomic position,» says Marad. (phys.org)
A study of Valleix et al. (2006) identified homozygous mutation of FOXE3 gene on 1p33 chromosome in three brothers with aphakia born by consanguineous parents. (doctor-info.website)