The phrase "homozygous state" refers to a genetic condition where an individual has two copies of the same gene variant. It means that the person inherits identical genetic information for a particular trait from both parents. Full definition
If a strain needs to be frozen down at homozygous state, a minimum of 5 males and 5 females is required. (infrafrontier.eu)
One example is a genetic defect which causes a blood clotting malfunction in the homozygous state. (sciencedaily.com)
Because patient XPCS2 was a hemizygote with mutant XPD protein (XPDG602D) expressed from a single allele, the corresponding mutation was expected to be viable in the homozygous state. (journals.plos.org)