«The basic message of our study is that DNA is not destiny,» says Sekar Kathiresan, MD, director of the Center for Human Genetic Research at Massachusetts General Hospital (MGH), senior author of the NEJM report. (sciencedaily.com)
In 2004 Guilherme Neves and Andrew Chess, now at the Center for Human Genetic Research at Massachusetts General Hospital, tracked the roles played by other genes on chromosome 21 — in this case using a fruit fly as the model. (scientificamerican.com)
Yet, SVs remain overlooked in human genetic research studies due to the limited power of short - read sequencing methods (exome and whole genome sequencing) to resolve large variants, which often involve repetitive DNA. (workcast.com)