Using mouse models that replicate the complexity of human hepatocellular carcinoma genetics, he is working on unravelling the mechanisms of regeneration and cancer development in the liver. (irbbarcelona.org)
The new study published in Cancer Cell by Sarris et al. shows that Smyd3 expression correlates with poor prognosis of human hepatocellular carcinoma. (fleming.gr)
HuH - 7 (human HCC), HepG2 (human hepatocellular blastoma), 293T (human embryonic kidney fibroblast), HeLa (human cervical cancer cells), NIH 3T3 (murine fibroblast), and HCT116 (human colon cancer) and its derived cell line HCT116 p21 − / − (kindly provided by Dr. B. Vogelstein, Howard Hughes Medical Institute, Chevy Chase and the Sydney Kimmel Comprehensive Cancer Center of the Johns Hopkins University School of Medicine, Baltimore, MD; ref. (cancerres.aacrjournals.org)