Any reassortant would likely need more genetic changes, such as ones that made the 1957 and 1968 strains better able to bind to human respiratory tract epithelial cells, the CDC team reports today in the Proceedings of the National Academy of Sciences. (sciencemag.org)
Its conidia production is prolific, and so human respiratory tract exposure is almost constant. (sanger.ac.uk)
We realized only later that concentrations of dust in the air were so high that they overwhelmed all the normal defenses of the human respiratory tract, and people inhaled ounces of dust into their trachea or their bronchi. (discovermagazine.com)