Studies over the past few years on hundreds of families with inherited breast cancer have traced BRCA1 to a region on the long arm of chromosome 17. (newscientist.com)
An estimated 50 % of inherited breast cancer cases (or about 5 % of all cases) are caused by mutations in the BRCA1 gene. (sciencemag.org)
On one side of the debate was a team led by breast cancer geneticist Mary - Claire King, who discovered the first inherited breast cancer risk gene, BRCA1. (sciencemag.org)