As is noted in our general instructions for preparing your initial manuscript, for initial submission we ask that, if possible, figures be included with text and tables in the manuscript file. (sciencemag.org)
We welcome initial submissions in any format and impose no limits on length, figures, or supplemental information. (genestogenomes.org)
However, the fact of the matter is, that most applicant's are denied on initial submission and require one or more appeals. (socialsecuritydisabilitylawyers.info)