While untreated pluripotent cells never expressed retinal markers (25 explants, npublished data), Noggin - treated explants expressed markers for rod and cone photoreceptors, as well as inner nuclear layer cells (Figure 7A — 7C; Table S5). (journals.plos.org)
Mosaic retinas stained for Calbindin (cones, K), R5 (Müller glia, L), GABA (horizontal and amacrine, M), and Islet - 1 (retinal ganglion and inner nuclear layer cells, N). (journals.plos.org)
In wild - type, retinal ganglion cell layer (GCL), inner nuclear layer (INL), inner plexiform layer (IPL), and nuclear layers of rod and cone photoreceptors are distinct, and rod outer segment (OS) is observed at the outer-most layer of the retina. (oist.jp)