Synergen, a biotechnology company based in Boulder, Colorado, stopped the trial involving 700 patients when interim analysis of data showed that the drug, called Antril, was not working. (newscientist.com)
Patient accrual was stopped ahead of schedule after an unplanned interim analysis found substantially improved survival rates in the arm receiving local therapy, matching similar findings in a parallel trial. (sciencedaily.com)
Thus, the claim by Cowtan and Way (2014) that the ERA - interim analysis shows a rapidly increasing cold bias in HadCRUT4 after 1998 does not apply to HadCRUT4v4 over the longer post 1978 period. (climateaudit.org)