Research from the Pediatric Cancer Genome Project has identified new mutations in pediatric brain tumors known as high - grade gliomas, including tumors like diffuse intrinsic pontine glioma pictured in this MRI. (stjude.org)
Diffuse intrinsic pontine gliomas account for 10 percent of all childhood central nervous system tumors. (danafarberbostonchildrens.org)
A study published in Molecular Cancer Research reveals that a tumor suppressor gene p16 is turned off by a histone mutation (H3.3 K27M), which is found in up to 70 percent of childhood brain tumors called diffuse intrinsic pontine glioma (DIPG). (sciencedaily.com)