The phrase "itch signals" refers to the messages sent by our nerves to our brain when we feel an urge to scratch or rub a certain area of our body to relieve an uncomfortable or tickly sensation. Full definition
Researchers have found how sensory nerve cells work together to transmit itch signals from the skin to the spinal cord, where neurons then carry those signals to the brain. (sciencedaily.com)
A treatment that could disrupt itch signaling at the level of the spinal cord would be «a tremendous boon,» he says. (sciencemag.org)
«We found that the TRPV1 channel that processes histamine - induced itch seems to work as a kind of molecular chaperone in the sensory neurons, helping the other channels process itch signals and transmit them to the spinal cord.» (sciencedaily.com)