Generally, it refers to involvement of large parts of the brain (or the whole organ), instead of identifiable changes confined to parts of the brain. (sciencedaily.com)
At the same time he was a mathematical physicist, and developed his theories in large part in order to comprehend the new findings of physics in the twentieth century. (religion-online.org)
Long - term recovery times are expected, due in large part because of the extent of damage done to the skin. (batonrougepersonalinjurylawfirm.com)