To find out, Jefferey identified two master genes that control lens development in the eyes of blind cave fish. (discovermagazine.com)
Different mutations in HSF4 have been reported to cause both human autosomal dominant and recessive cataracts [97 — 99] and studies in mice have shown HSF4 is required for normal fibre cell differentiation during lens development [100, 101]. (cgejournal.biomedcentral.com)