The increased leptin secretion that occurs with increased weight normally feeds - back to the hypothalamus as a signal that there are adequate energy (fat) stores. (verywellhealth.com)
Additionally, circadian misalignment is associated with alterations in cortisol and leptin secretion in relation to wake - sleep and feeding - fasting cycles causing further aggravating dysregulation of glucose and energy homeostasis (258, 259). (academic.oup.com)
Matthew Ricci, Ph.D. - VP / Science Director Dr. Ricci received his Ph.D. in Nutritional Sciences from Rutgers University in 2000, where he studied leptin secretion from human adipose tissue in vitro with Susan K. Fried, Ph.D.. (researchdiets.com)