"Lesion formation" refers to the process of an abnormality or damage occurring on an organ or tissue in the body. It is when an area within the body is affected and shows signs of injury, disease, or any structural change. Full definition
Conklin also said that chronic exposures to smokeless tobacco extracts, mainstream cigarette smoke, acrolein, or e-cigarette aerosol enhanced atherosclerotic lesion formation in a mouse model of atherosclerosis. (aaas.org)
Scientist at the Linus Pauling Institute and College of Veterinarian Medicine at Oregon State University and the Department of Medicine at the University of Washington found that lipoic acid supplements reduced atherosclerotic lesion formation in two types of mice that are widely used to study cardiovascular disease, by 55 percent in one group, and 40 percent in the other group. (naturalhealth365.com)
However, when the animals were relocated to a new facility, the frequency of lesion formation decreased to almost zero. (sciencedaily.com)