Cells that express high levels of the transcription factor myc up - regulate glutaminase expression more than 10-fold [105]. (biochemj.org)
T - DOGGs can be made drug - inducible using the rTetR system, but Cre - DOG lacks the toxicity that can be seen with high levels of transcription activation domains. (blog.addgene.org)
The group also found that the expression level of transcription factor Bach2 in germinal - center B cells with lower affinity was significantly high, and that this high expression of Bach2 was important for memory B cell differentiation. (sciencedaily.com)