Phrases with «lineage commitment»

Lineage commitment refers to the process when a stem cell or precursor cell decides to specialize into a specific type of cell, such as a blood cell or a nerve cell. It is the point at which a cell takes on a specific fate and function, determining what type of cell it will become in the body. Full definition

Sentences with «lineage commitment»

  • In addition, the researchers showed that Cbf - beta maintains the osteoblast lineage commitment in two ways — through the Wnt paracrine pathway to affect nearby cells and through endogenous signaling within the cell to suppress adipogenesis gene expression. (sciencedaily.com)
  • Regulation of lineage commitment distinct from positive selection. (cancerresearch.org)
  • In this case, the two ICMs were not equal and high - resolution RNA sequencing indicated that they were at different stages of development; the smaller one was in the earliest stages of cell lineage commitment, while the bigger one had already differentiated to some extent. (sciencedaily.com)
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