Dr. Jiang found that LPCAT3 deficiency significantly reduces polyunsaturated PC levels in the plasma membrane of the cells that line the intestines, which in turn reduces lipid absorption and decreases levels of lipids (cholesterol, triglyceride, and phospholipid) in circulation. (sciencedaily.com)
Investigators studied bile production and lipid absorption in mice deficient in the KLF15 protein. (sciencedaily.com)
«These bacteria are part of an orchestrated series of events that make lipid absorption more efficient,» said the study's senior author, Eugene B. Chang, MD, the Martin Boyer Professor of Medicine and director of the NIH Digestive Diseases Research Core Center at the University of Chicago Medicine. (sciencedaily.com)